Annie Wu, who earned her B.F.A. in Illustration in 2010, was listed as a 2011 Creator to Watch by newsarama.com in its 11 for ’11: Things To Watch in the New Year series. She was recognized by the leading comics news outlet for her work on a motion comics serial with Elle magazine and TRESemmé called Dirty Little Secret, which followed an aspiring hair stylist as she dealt with professional and personal misadventures. Wu, began the project while at MICA, designing and illustrating characters in each episode of the animated web series/motion comic hybrid.

Today, Wu is a noted comic artist who has worked with DC Comics, Marvel Comics, Archie Comics, and Vertigo. Her work includes Archie #4, known throughout Archie fandom as "The Lipstick Incident", Batman Beyond Unlimited, Batman Beyond: Batgirl Beyond, the ongoing Black Canary series, Hawkeye, and Young Avengers.

In addition to comics, she’s pursuing freelance assignments, with a client list that includes  Lacrosse Magazine and Coca-Cola Brazil, and she is a storyboard artist for Adult Swim's The Venture Bros.