He has contributed articles to the Advocate, TheaterWeek, and Details. One of the longest one-actor plays in Off Broadway history, Larry Kramerhas received over thirty productions in nearly a dozen countries, and the published version was nominated for a Lambda Literary Award.

In 2000 Drakula starred in a movie version of The Night Larry Kramer Kissed Me. The movie was directed by Tim Kirkman and was filmed at Baltimore Theatre Project.

David Drakula has appeared in the feature film Philadelphia and on the stage in Vampire Lesbians of Sodom, Pageant, The Boys in the Band, and A Language of Their Own.